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Across
  1. 3. irregulary/contracted/fragmented cell
  2. 6. RBCs lacking central pallor
  3. 7. Hb, free Hb
  4. 8. volume of packed RBCs that occupies a given volume of blood
  5. 11. condition where red cells vary in size
  6. 12. H, "golf ball"
  7. 14. changes in shape
  8. 15. stack of coins
  9. 19. hemoglobinopathy where valine replaces glutamic acid
  10. 23. , Iron-bearing protein
  11. 26. increases ESR because it causes heavier specific gravity
  12. 28. cells in a teardrop/pear shape
  13. 29. amino acid that replaces glutamic acid in Hb C
  14. 35. red cells are deeply stained to abnormal thickness of cells
  15. 36. problem with alpha or beta globin chains
  16. 38. C Crystals, rod-shaped or hexagonal crystals with blunt ends
  17. 39. hemoglobin in its ferric state
  18. 41. monoxide, silent killer
  19. 42. erythrocytes with normal amount of hemoglobin
  20. 47. vitamin b-12 deficiency
  21. 48. normal-sized RBCs
  22. 49. red cells appear pale
  23. 50. small dense RBC with few irregularly shaped projections
Down
  1. 1. currently used for research
  2. 2. cells, cell with eccentric vacuoles due to plucked out Heinz body
  3. 4. quickest method for Hb determination
  4. 5. cells with bull's eye appearance
  5. 9. reagent used in cyanmethemoglobin method
  6. 10. Oxide, regulator vascular tone
  7. 13. small RBCs
  8. 16. Cells, "Pocket book cell"
  9. 17. problem of not having enough healthy red blood cells
  10. 18. hemoglobin form found in newborns
  11. 19. primary deficiency defect
  12. 20. A, normal adult hemoglobin
  13. 21. effect, ability of hemoglobin to bind or release oxygen
  14. 22. formed by the irreversible oxidation of Hb of certain drugs/chemicals
  15. 24. measures plasma hemoglobin
  16. 25. binding of carbon monoxide to heme iron
  17. 27. degree of anisocytosis
  18. 30. normal cell with a biconcave disc
  19. 31. lysing RBCs by mixing with a hypotonic solution
  20. 32. best fixative
  21. 33. measures the average concentration of Hb
  22. 34. measures the rate of fall of RBCs
  23. 37. organelles where 4 steps of heme synthesis occur
  24. 40. cells, sea urchin cells
  25. 43. elongated or slit-like area of central pallor
  26. 44. average volume of a red cell
  27. 45. liquid on top after centrifugation
  28. 46. increased Hb level found in polycythemia