Kawasaki Disease

1. What gender group is most affected?
5. The etiology of KD remains ______.
6. KD peaks in the _____ age group.
7. __________ is obtained at the time of diagnosis as a baseline measurement to assess for coronary aneurysm or inflammation.
9. The acute myocarditis of KD may progress to ______ ventricular dysfunction.
10. The predominant theory is a genetic predisposition to the development of autoimmune response to inhaled viruses such as _________, coronavirus, or Epstein-Barr virus.
12. In the US which race is affected twice as often?
13. _______ of the intestinal microbiome and intestinal permeability may play a role in the etiology of KD.
14. The _______ and adaptive immune system responses in KD include the release of multiple inflammatory cytokines.

2. In the acute phase a child with typical KD has fever, conjunctivitis, oral changes such as __________ tongue, rash, erythema of plans and soles, and lymphadenopathy, and is often irritable.
3. Kawasaki shock syndrome is characterized by __________, hypotension, poor perfusion, coagulopathy, and anemia.
4. _________ phase begins when the fever ends and continues until clinical signs have resolved.
8. Kawasaki Disease (KD) is the leading cause of acquired heart disease among children in the US, but is far more prevalent in ______ countries such as Japan and Korea.
11. ________ are activated, and vessels develop scarring, intimal thickening, calcification, and stenosis.