Kidney P. 8

2. The complement components that form the destructive membrane attack complex
4. The complement system component that acts as a chemo-attractant for neutrophils
5. The abbreviation for the basement membrane, a target of direct antibody attack
6. A feature of nephrotic syndrome where the liver secretes excess lipids
8. The blood cells whose function is damaged by high urea levels, leading to bleeding
11. The underlying cause of most glomerular diseases discussed in the lecture
12. The syndrome characterized by massive proteinuria, edema, and podocyte dysfunction
14. A neuromuscular manifestation of uremia involving a lack of coordination
15. The syndrome characterized by an acute onset, hematuria, and inflammation

1. A cardiovascular manifestation where urea aggravates the sac around the heart
3. The layer on the inner surface of the basement membrane where immune complexes can deposit
4. The immune system cascade triggered by antibody deposition in the glomerulus
6. The hallmark feature of nephritic syndrome, meaning blood in the urine
7. An involuntary hand-flapping tremor seen in severe uremia
8. The hallmark feature of nephrotic syndrome, meaning massive amounts of protein in the urine
9. The layer on the deep side of the basement membrane where immune complexes can deposit
10. The location where immune complexes can deposit, in addition to subepithelial or subendothelial layers
13. The key pathophysiology that marks the nephrotic syndrome