KN Onc Crossword

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Across
  1. 4. This monoclonal antibody may cause the reactivation of Hep B.
  2. 5. This "-mib" requires a minimum of 72 hours between doses.
  3. 7. This Tyrosine Kinase inhibitor must be dosed with Capecitabline.
  4. 8. This monoclonal antibody requires a pregnancy test prior to first treatment.
  5. 10. This a PI3K-delta inhibitor with a black box warning of severe diarrhea/bowel perforation/heptotoxicity.
  6. 13. This is a VEGF inhibitor as known as Zaltrap.
  7. 17. This monoclonal antibody has the side effects of HI perforation, HF, delayed wound healing and possible hyperglycemia.
  8. 19. This "-mib" is the first oral version of this class with major CYP3A4 interactions.
  9. 20. This is a "-degib" has a possible side effects including muscle pain/myalgia/rhabdo.
Down
  1. 1. This tyrosine Kinase inhibitor may need to be adjusted for renal impaired patient
  2. 2. This mTOR is given by mouth daily.
  3. 3. The use of certain medications concurrently with pH modifying drugs may decrease this drug's aborptions
  4. 6. This is a Histon Deacetylase Inhibitor that s given IV during the first week of a three week cycle.
  5. 8. This mTOR is given once weekly via IV.
  6. 9. This "-mib" may cause hyperglycemia.
  7. 11. This a PARP Inhibitor with secondary malignancies.
  8. 12. This is a "-stat" is given by mouth every other day for weeks 1 and 2 with off week 3.
  9. 14. This is a Hedgehog Pathway Inhibitor does not cause ALT/AST elevations.
  10. 15. This monoclonal antibody requires monitoring of vital signs during the 1st hour after fusion then every eight weeks
  11. 16. This is a CDK 4 and 6 Inhibitor that is given on a 3 week on and 1 week off cycle.
  12. 18. This is a "-stat" given by mouth each day.
  13. 21. This Trrosine Kiase Inhibitor may cause pleural effusion as one of its side effects.