Across
- 2. found in amanita muscaria mushrooms; a GABA-A agonist (8 letters)
- 6. a "regenerator" of cholinesterase activity; competes with anti-cholinesterases
- 7. a mAChR antagonist responsible for preventing motion sickness
- 9. a broad mAChR agonist; agonizes m1, m2, m3, m4, & m5
- 12. (abbreviation) transporter responsible for pumping 1 molecule of ACh into a vesicle
- 16. a recently discovered drug that enhances muscarinic agonist binding
- 17. a m3 mAChR antagonist
- 20. (abbreviation) enzyme that degrades ACh into acetate and choline
- 21. a broad mAChR antagonist; antagonizes m1, m2, m3, m4, & m5
- 22. a m2 & m4 mAChR antagonist
- 23. (abbreviation) enzyme that catalyzes the synthesis of acetyl CoA and choline into ACh
- 24. a m2 mAChR antagonist
- 26. an irreversible organophosphate, also a WMD
Down
- 1. a long acting anti-cholinesterase; can be broken down by the body
- 3. a long acting organophosphate insecticide (8 letters)
- 4. a m4 mAChR antagonist
- 5. found in amanita muscaria mushrooms; a agonist of m1 and m5 mGluRs
- 8. a short acting anti-cholinesterase; can be broken down by the body
- 10. a long acting organophosphate insecticide (9 letters)
- 11. a m1 mAChR antagonist
- 13. block cholinesterase activity; cannot be broken down by the body
- 14. irreversible organophosphate insecticide banned in the US because it affected the American Eagle population
- 15. a m1 mAChR agonist
- 18. found in amanita muscaria mushrooms; a GABA-A agonist (9 letters)
- 19. blocks the transport of ACh into the vesicle
- 25. a mAChR antagonist that can treat mushroom poisoning and reduce secretions; royal Egyptians used this extract to dilate their pupils