L6 Heart Failure: Heart Failure with Reduced Ejection Fraction (HFrEF) Treatment

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Across
  1. 2. Combined with sacubitril to block angiotensin II receptor in heart failure.
  2. 5. Aldosterone antagonist used to reduce mortality in HFrEF.
  3. 7. SGLT2 inhibitor used to treat heart failure, regardless of diabetic status.
  4. 8. Dinitrate Reduces preload by dilating veins in heart failure patients.
  5. 10. Blockers Reduces heart rate and improves survival in heart failure patients.
  6. 11. Loop diuretic commonly used for fluid retention in heart failure.
  7. 14. Antagonist Prevents sodium retention and potassium excretion in HFrEF.
Down
  1. 1. SGLT2 inhibitor that reduces heart failure hospitalization.
  2. 3. Vasodilator used for heart failure patients intolerant to RAAS inhibitors.
  3. 4. Stimulates guanylate cyclase to reduce heart failure hospitalization.
  4. 6. Diuretics Promotes sodium and fluid loss to manage fluid overload.
  5. 8. Reduces heart rate by inhibiting the funny current in pacemaker cells.
  6. 9. Reduces sodium retention and vasoconstriction by inhibiting neprilysin.
  7. 12. Cardiac resynchronization therapy device used for heart failure patients with wide QRS.
  8. 13. Inhibitors First-line medication for heart failure patients with LVEF < 40%.