Lecture 8 and 9

2. molecule that can help deactivate T cells
4. ligand for PD-1
5. these T cells express both CD4 and CD8
6. CTLA-4 and PD-1 function as this type of protein that decommissions T cells
8. Do you have receptors that recognize one of the self MHC molecules which I am expressing on my surface?
11. cell that is characteristically star shaped
12. protein that's prominently displayed on the surface of CTLs
14. another level of protection against autoimmunity
16. a way of eliminating obsolete T cells after they have been re-stimulated many times
18. transcription factor that drives expression of many tissue specific antigens
20. Do you recognize any of the self peptides displayed by the MHC molecules on my surface?
21. binding partner for Fas ligand
23. T cells that help protect us from autoimmunne disease; subset of CD4 T cells selected to become these cells
25. Cell that asks T cells questions
27. T cells learn tolerance of self in the thymus

1. these proteins give each organ or tissue type its identity
3. Cell that tests T cells for tolerance of self
7. a "neutered" T cell
9. Cells that stop displaying either CD4 or CD8
10. T cell that dampens the immune response
13. the outer region of the thymus
15. at least 25% of all B cells in mice take advantage of this "second chance"
17. self eating
19. NK cells destroy cells that don't display class I MHC molecules on their surface
22. central region of the thymus
24. B7 molecules plug into these receptor proteins on T cells
26. gene that conferrs nTreg cells their properties