Lipids, lipid control and clinical biomarkers

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Across
  1. 5. hormone which is known to induce lipolysis
  2. 6. disease in which the inside of an artery narrows due to the build up of plaque
  3. 8. type of fatty acids that are produced by an industrial process
  4. 9. hormone which activates HMG CoA reductase
  5. 12. lipoprotein particle that is the lowest in density and the largest in size
  6. 15. biological matrix often used for the measurement of clinical biomarkers
  7. 16. watery mixture of organic and inorganic compounds that act as emulsifying agents
  8. 20. abnormally elevated levels of any or all lipids or lipoproteins in the blood
  9. 21. a lipid made of glycerol, two fatty acid tails and a phosphate-linked head group
  10. 23. primary function is the transportation and delivery of fatty acids, TAG and cholesterol to and from target cells
  11. 24. type of fatty acids that possess no double bonds
  12. 25. the metabolism of LDL occurs through ___________-mediated endocytosis
  13. 26. haemoglobin, gold standard biomarker for diagnosis and monitoring of blood glucose regulation and diabetes
  14. 27. measurable indicator of the presence or severity of a disease state
Down
  1. 1. disorder caused by increased secretion of cholesterol into bile
  2. 2. one of the seven controllable risk factors for acquired hyperlipidaemia
  3. 3. type of obesity that often leads to insulin resistance
  4. 4. classification of hyperlipidaemia resulting from another underlying disorder
  5. 7. fatty acids that must be ingested as they are not synthesized by the body
  6. 10. most important class of dietary fats (TAG)
  7. 11. primary function is to provide cholesterol to peripheral tissues (or return it to the liver)
  8. 13. CoA-reductase, control point for cholesterol synthesis
  9. 14. macromolecule attached to membrane proteins forming glycoproteins
  10. 17. cell type whose major function is the storage of triacylglycerols
  11. 18. CRP and IL-6 are common biomarkers for this disease state
  12. 19. metabolic pathway through which lipid triglycerides are hydrolysed into glycerol and fatty acids
  13. 22. characteristic steroid alcohol of animal tissues that is a structural component of cell membranes
  14. 24. type of drug used for the treatment of elevated total cholesterol which competitively inhibits HMG CoA-reductase