LO 12: Auto-Immunity

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Across
  1. 6. What genetic variation accounts for roughly 15% of Crohn's disease?
  2. 8. This type of selection occurs when a thymocyte expresses a TCR that weakly recognises self-MHC molecules.
  3. 10. Gluten is predominately composed of glutelin and what other protein?
  4. 11. Which amino acid is primarily responsible for making gluten hard to digest?
  5. 12. The components of gluten are ____ resistant.
Down
  1. 1. What antibody is used to test for coeliac disease?
  2. 2. Rheumatic Fever is caused by ____?
  3. 3. This process triggers autoimmunity due to pathogenic antigens looking similar to host antigens.
  4. 4. This variant of the MCH class II is the main genetic risk factor for coeliac disease.
  5. 5. Your risk of getting multiple sclerosis is increased 32-fold when infected with this virus.
  6. 7. Autoimmunity and inflammatory diseases are _____ due to their multiple triggers.
  7. 9. The major S. pyogenes antibodies are N-acetyl-βD-glucosamine and ____?