Malignant lymphoma, Dr. Kurzer

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Across
  1. 4. Reed-sternberg cells are cd30 and cd___ positive, and cd45 negative, write out the word
  2. 7. a characteristic translocation of burkitt lymphoma is c-myc, t(_;14), write out the number
  3. 8. Most common adult non-hodgkins lymphoma
  4. 10. anaplastic large cell lymphoma is characterized by ___ rearrangements, ie t(2;5)
  5. 12. Abnormal follicles in follicular lymphoma are closely packed and lack mantles, polarization, and ___
  6. 13. Follicular lymphoma arises from ___ B cells
  7. 14. Endemic ___ lymphoma is associated with EBV infection, classically presents as a jaw mass in an African child. The sporadic form can present as an abdominal mass
Down
  1. 1. In Hodgkins lymphoma, ___ cells secrete cytokines that cause accumulation of inflammatory cells like lymphocytes, neutrophils, eosinophils, which constitute the majority of the mass
  2. 2. Management option in indolent follicular lymphoma
  3. 3. ___ lymphoma diffusely stains with CD20
  4. 5. Lymphoma with aggressive behavior, treatment involves a combo of chemo plus anti-cd20 monoclonal antibody
  5. 6. t(14;18) in ___ lymphoma causes overexpression of BCL2, which stops apoptosis
  6. 9. As opposed to other lymphomas, ___ lymphoma has contiguous spread
  7. 11. On histology, burkitt lymphoma is said to have a "___" appearance, due to tissue macrophages containing ingested nuclear debris