MCDB 3150 - Cancer Crossword

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Across
  1. 3. Guardian of the Genome
  2. 9. Abnormal increase in the number of normal looking cells in a tissue
  3. 10. uncontrolled cancer cells that grow as a mass
  4. 12. The “wheel of death”
  5. 13. Protected from the DNA damage response due to their T-loop structure
  6. 15. When cancer cells invade and spread to surrounding tissue
  7. 17. Key regulator of angiogenesis, its initials stand for a factor that promotes the formation of blood vessels.
  8. 20. Arises from cells derived from mesenchyme
  9. 21. A complete loss of differentiation in a tissue
  10. 24. Cancer of the blood
  11. 25. Cancer cells causing the immune cells to not function properly
  12. 26. Cytochrome C is released from the ______
  13. 28. Genes that, when hyperactive, promote cancer development
  14. 29. Cancers of cells originating and residing in the lymphatic system
Down
  1. 1. Chemical DNA damage that cleaves N‐glycosidic bonds
  2. 2. Class of enzymes involved in DNA supercoiling
  3. 4. A group of proteases capable of eating a cell from within; activated by cytochrome C
  4. 5. The formation of new blood vessels, crucial for tissue growth and repair
  5. 6. Associates with foreign bodies to degrade in the lysosome
  6. 7. the surname of the scientist who discovered the first human oncogene (Ras)
  7. 8. Universal factor driving cells into Metaphase
  8. 11. Cells or tissues with normal oxygen levels
  9. 12. A feature of cancer cells that describes how they divide independently of other cells
  10. 14. programmed cell death
  11. 16. Regulate CDKs
  12. 18. The study and diagnosis of a disease
  13. 19. A tumor with cells that have the potential to invade nearby tissues and spread to other parts of the body
  14. 22. Activated mostly by double-stranded breaks
  15. 23. Antibody-producing cells
  16. 27. Cells or tissues with low oxygen levels