Medical innovations

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Across
  1. 1. be in charge of (a company, establishment, or undertaking)
  2. 4. open out (something) so as to extend its surface area, width, or length.
  3. 6. the state or fact of continuing to live or exist, typically in spite of an accident, ordeal, or difficult circumstances.
  4. 8. refuse (an invitation or offer).
  5. 10. a series of actions or steps taken in order to achieve a particular end.
  6. 11. arrange systematically in groups; separate according to type, class, etc.
  7. 12. made or produced by human beings rather than occurring naturally, especially as a copy of something natural.
  8. 13. a person who is among the first to explore or settle a new country or area.
  9. 14. identify the nature of (an illness or other problem) by examination of the symptoms.
Down
  1. 2. based on untested ideas or techniques and not yet established or finalized.
  2. 3. a particular form of procedure for accomplishing or approaching something, especially a systematic or established one.
  3. 5. a person or thing that takes the place of another.
  4. 6. a small part or quantity intended to show what the whole is like.
  5. 7. drive or force (a liquid, especially a drug or vaccine) into a person or animal's body with a syringe or similar device.
  6. 9. an instrument or device used for observing, checking, or keeping a continuous record of a process or quantity.