Across
- 1. A hypoglycemic agent that activates insulin-mediated potassium transport into cells, exacerbating hypokalemia in overdose scenarios
- 6. These adrenergic receptor modulators, specifically targeting the beta-2 subtype, are utilized to induce bronchodilation, thereby facilitating improved airflow and respiratory efficiency in individuals suffering from constrictive pulmonary disorders
- 8. Unlike most antifungals, this drug disrupts fungal membranes by binding to ergosterol, and is known to lower potassium levels significantly, which can lead to hypokalemia as a common side effect
- 9. These class of medications that suit them nickname like "water-pushers" targets the thick ascending limb of the loop of Henle by inhibiting the Na⁺/K⁺/2Cl⁻ carrier to stop sodium from being reabsorbed, which causes a BIG loss of potassium, so electrolyte levels need to be watched closely
- 10. This platinum-based chemotherapeutic agents, renowned for there efficacy against various malignancies, can induce dose-limiting nephrotoxicity characterized by renal tubular dysfunction and a progressive decline in glomerular filtration rate (GFR)
Down
- 2. prescribed for patients with persistent constipation despite fiber and osmotic laxative use, work by increasing endogenous prostaglandin release from the intestinal mucosa, leading to enhanced colonic fluid and electrolyte secretion, and boosting intestinal motor activity
- 3. these group of medications that fit with such descriptions like "water pill " hangs out in the distal convoluted tubule of nephron , blocking sodium from re-entering, making sure fluid exits
- 4. a carbonic anhydrase inhibitor, utilized in managing intraocular pressure in glaucoma patients, also serves as a diuretic to alleviate edema in congestive heart failure, and is employed in the treatment of specific seizure types and the prevention of altitude sickness
- 5. It is a methylxanthine derivative and bronchodilator used to alleviate symptoms of asthma, bronchitis, emphysema, and other respiratory issues
- 7. These pharmacologically engineered compounds, which emulate the physiological actions of endogenous corticosteroids, are frequently administered to mitigate inflammatory responses and suppress the immune system in various medical conditions