Memory Cross Word puzzle

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Across
  1. 2. Molecular basis for innate memory reprogramming
  2. 5. Determines the quality and longevity of T cell memory formation
  3. 6. Long-term protection involving class switching and affinity maturation
  4. 9. Process improving antibody affinity in germinal centers
  5. 11. Cytokine important for survival of memory T cells
  6. 13. Long-lived memory T cells that reside in lymphoid organs
  7. 14. Type of T cell generated during a primary response
  8. 15. Cells providing activation and costimulatory signals to T cells
  9. 17. Cytokine required for NK cell memory induction
  10. 19. Small antigen that is not immunogenic alone
  11. 20. Altered in memory T cells to favor rapid activation
  12. 21. Enzymes secreted by NK cells to induce apoptosis in target cells
  13. 22. Defining feature of the adaptive immune system
  14. 23. Innate immune memory caused by epigenetic and metabolic reprogramming
  15. 25. Large immunogenic molecule that helps induce response to a hapten
  16. 26. Cells that secrete antibodies during secondary responses
  17. 28. Process changing antibody isotype during B cell activation
  18. 30. Mechanism making nonimmunogenic molecules immunogenic when linked
  19. 31. Type of modification involved in innate immune training
  20. 32. Innate immune cells capable of developing trained immunity
Down
  1. 1. T cells that remain in tissue sites for rapid protection
  2. 3. Helper T cells critical for B cell memory development
  3. 4. Cytotoxic protein upregulated in memory NK cells
  4. 7. Receptor important for NK cell trafficking in memory formation
  5. 8. Memory-like T cells generated without antigen exposure
  6. 9. Response that is faster and stronger due to immune memory
  7. 10. Cytokine that maintains memory CD8 T cells
  8. 11. Cytokine that enhances NK cell activation with IL12 and IL15
  9. 12. T cells that circulate in non-lymphoid tissues
  10. 16. T cells capable of self-renewal and generating all other memory subsets
  11. 18. Cytokine produced by memory NK cells upon reactivation
  12. 21. Site of B cell proliferation and differentiation during memory formation
  13. 24. Innate lymphocytes that can exhibit antigen-specific memory
  14. 27. Transcription factor that regulates memory T cell metabolism
  15. 29. Type of T cell that has not yet encountered its antigen