Metal Ions in Pharmaceutical Chemistry

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Across
  1. 4. Metals with no biological role that cause harm
  2. 7. Metals required for biological functions
  3. 8. Common geometry for many metal complexes
  4. 11. Inhibits carbonic anhydrase for glaucoma
  5. 12. Reaction that activates cisplatin by replacing chloride
  6. 13. Metal involved in enzyme active sites
  7. 14. Protein that carries oxygen using Fe²⁺
Down
  1. 1. Challenge in delivering metal-based drugs
  2. 2. Molecules that attach to metals in complexes
  3. 3. Future direction for targeted metal-based delivery
  4. 5. Ability to target specific metals without side effects
  5. 6. Removal process for excess metal ions
  6. 9. Strategy where ligands bind metals to form complexes
  7. 10. Gene-editing tool proposed for metal disorders