Metoprolol

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Across
  1. 4. Lowers risk of future cardiac events
  2. 5. Cardioselective beta1 receptor blocker
  3. 6. Used to treat chronically elevated blood pressure
  4. 9. Reverses severe slow heart rate toxicity (Antidote)
  5. 11. Contraindicated in abnormally slow pulse
  6. 14. Sudden stopping may trigger chest pain or infarction
  7. 15. Respiratory condition requiring caution
  8. 17. Possible at high doses from beta2 effect
  9. 18. May occur when standing due to BP drop
Down
  1. 1. Check before giving each dose
  2. 2. Can cause symptomatic low blood pressure
  3. 3. Combination increases risk for heart block (Drug-drug interaction)
  4. 6. Often given with ACE inhibitor or ARB therapy
  5. 7. Reduced energy commonly reported by patients
  6. 8. Concurrent use intensifies cardiac suppression (Drug-drug interaction)
  7. 10. Improves oxygen supply-demand balance of the heart
  8. 12. May hide warning signs of hypoglycemia
  9. 13. Dose reduction required over 1 to 2 weeks
  10. 16. Withhold medication if heart rate is too ___