Across
- 3. Inhibits viral replication
- 5. Displays antigens to B cells
- 10. Process of coating particles for phagocytosis
- 11. TLR repeated motif protein
- 12. Activates integrins and chemokinesis
- 15. Low weight regulatory proteins or carbohydrates
- 18. Constant and Variable Ig domains linked
- 20. Creates a pore
- 22. Cell that does not express CD3
- 24. Binds to MHC1
- 27. Targets Helminth parasites
- 28. The V domain of Ig
- 33. This cleaves Ig
- 34. Phosphorylates a key tyrosine residue
- 35. Host cell pattern recognition receptors recognize
- 37. Immature Dendritic cells in skin
- 39. Another name for Antibodies
- 42. Carbohydrate ligand
- 43. Mechanisms in place prior to infection
- 48. Conserved PRRs
- 51. IgM expressing B cell is
- 53. Encoding only on inherited alleles
- 56. Conversion of native proteins into MHC associated peptides
- 58. Type of T cells that have not been in contact with antigen
- 62. Activate macrophages
- 63. Gene that promotes expression of tissue-specific antigens in thymic medullary cells
- 64. Produced epithelial cells
- 65. Enzyme that recognizes specific DNA sequence in B cell gene and cleaves it
- 66. Receptor that transports IgA
- 67. Phosphorylates transcription factor STATs
- 69. Functional antigen receptors are produced in immature B cells by gene
- 72. Detect antigen in skin and mucosa
- 73. Display of peptides on surface
- 75. TCR D and J genes contribution
- 76. T cells undergo proliferation
- 77. Delivered through CTL pore
Down
- 1. Bind to cell adhesion molecules
- 2. Contains antimicrobial molecules
- 4. Stem cell that give rise to T and B cells
- 6. Pathway initiated by soluble mannose-binding proteins
- 7. Cleaves C3 into C3a and C3b
- 8. In B cells, proteins that mediate recombination are called
- 9. CD8+T cell binds to this APC site
- 13. Strength of attachment of antibody to antigen considering all epitopes
- 14. Bind to MHC
- 16. T cells produce cytokines and receptors such as IL-2
- 17. Movement from tissue to blood stream
- 19. Chemokines IL1, IL-12 IL-23
- 21. Organ-specific autoimmunity is averted
- 23. Family of migration regulating proteins
- 25. Long lived T cells
- 26. Response that blocks infections and eliminate extracellular microbes
- 29. CTL recognition results
- 30. Strength of single binding between antibody and epitope of an antigen
- 31. CD4+T cell binds to this APC site
- 32. State of resistance to disease or pathogen
- 36. B cells that may have IgA, IgG or IgE membrane IGs
- 38. T cells unable to recognize self-antigens disease
- 40. IgA function in this region
- 41. Large granular lymphocyte
- 44. Microbes that develop Th17 T cells
- 45. Peptides in MHC Class 2 transportation location
- 46. T lymphocytes mature here
- 47. Th2 effect T cell role in disease
- 49. T Cell origin
- 50. Specialized cells deep in the epithelial crypts in the intestines
- 52. T cells that travel to sites of infection in peripheral tissue
- 53. These cells are removed in the thymus
- 54. CTLA-4 binds to B7 of activated T cells to deliver _______ signals
- 55. Igα and Igβ disulfide linked
- 57. Antibody that activates the classical pathway
- 59. LPS stimulates this on endothelial cells
- 60. Microbes that develop Th1 T cells
- 61. Peptides in MHC Class 1 transportation location
- 68. Response to infection
- 70. The initiator of mutations in class switching of heavy chain
- 71. Outer layer of gram-positive bacteria
- 74. Proliferated progeny cells
