Across
- 5. this signals protein molecules that modulate the immune response and promote blood flow to the site of injury or infection
- 6. are found throughout the body; originate from monocytes
- 7. (two words) stimulate development of adaptive immunity in cells that contact the environment (skin); agranulocyte; have long arms for capturing and presenting antigens to the immune system
- 10. the ingestion and breakdown of foreign substances, including bacteria
- 11. agents that cause disease, infect wide variety of animals, including humans (some bacteria and viruses)
- 12. triggers blood vessels to dilate and become more permeable to tissues
- 14. consists of 30 proteins that are activated by substances on microbe surfaces
- 15. a type of leukocyte/white blood cell
Down
- 1. circulates in the blood and are attracted by signals from infected tissues; first responders to the infection
- 2. circulate within hemolymph and carry out phagocytosis (there is no blood); also release antimicrobial peptides that disrupt the plasma membrane of fungi and bacteria
- 3. discharge destructive enzymes; granulocyte; involved in allergic and anti-helminth responses
- 4. (two words) a life-threatening condition caused by an overwhelming inflammatory response (40% average mortality rate)
- 8. traps and allows the removal of microbes
- 9. provide innate defense, interfering with viruses and helping activate macrophages
- 13. a systematic inflammatory response triggered by substances released by macrophages