Midterm #1 Review

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Across
  1. 3. this intracellular protein is expressed on the surface of endothelial cells that line blood vessels and stops integrin from rolling
  2. 5. _______ selection is the principle that when the receptors on B or T cells recognize their cognate antigen, they are triggered to proliferate
  3. 7. hyperactivation of macrophages can be induced by these molecules, LPS and _______
  4. 9. neutrophils bind to selectin using _____ which slows them down
  5. 11. this protein is produced and stored in the neutrophil
  6. 14. this protein is a cytokine that can activate a resting macrophage into its primed state
  7. 16. the system that contains about 20 different proteins in the liver that work together to destroy invaders
  8. 17. monocytes that are matured can either be macrophages or ________
  9. 18. ______ group and amino groups are able to initiate the complement cascade
  10. 19. these nodes function as a meeting place where T and B cells, APCs, and antigens interact and activate the adaptive immune system
Down
  1. 1. this cytokine can kill tumor cells and virus infected cells and help activate other immune cells
  2. 2. hormone like proteins that are produced and secreted by macrophages that can communicate between cells
  3. 4. the structure on an antibody that binds to receptors and determines its class
  4. 6. when stem cells are able to divide into two daughter cells to make more stem cells
  5. 8. to "decorate" fragments of complement proteins or with antibodies on their invaders
  6. 10. the Fab region of an antibody binds to a specific _______
  7. 12. these receptors can be found on the outer surface of phagocytic cells or in the membranes of phase-lysosomes
  8. 13. when this dendritic cell becomes infected, it releases Type I interferons that work to warn other cells and slow down viral replication
  9. 15. granulocytes include neutrophil, basophil, and _______
  10. 17. a protein on human cells that accelerate the destruction of the convertase C3bBb