MODULE 1: CROSSWORD PUZZLE

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Across
  1. 3. farmer who inoculated his wife with vaccinia virus. First record of anyone using vaccinia virus to “protect” against smallpox
  2. 5. pioneer in the humoral theory of immunity
  3. 8. histiocytes
  4. 10. received a letter from a trade in China which reported a method that would prevent a future smallpox disease
  5. 13. used serum to treat diseases and discovered immunity against diphtheria and tetanus
  6. 15. Devised an agglutination reaction for the diagnosis of typhoid fever.
  7. 17. Monocytes are transformed into this once it reaches tissues
  8. 19. Discovered precipitins
  9. 22. benign disease caused by a virus closely related to the smallpox virus
  10. 27. Kupffer cells.
  11. 30. Least numerous of the WBCs found in peripheral blood, representing less than 1% of all circulating WBCs.
  12. 33. year when the Worl Health Assembly officially declared “the world and its people” free from endemic smallpox.
  13. 34. the process of controlling infection and also called "inoculation"
  14. 35. all that can cause immune response
  15. 36. Demonstration of cutaneous hypersensitivity
  16. 38. also known as Cattle Plague
  17. 39. Are concerned with humoral immunity
  18. 40. king of immune system
Down
  1. 1. osteoclasts
  2. 2. make a pathogen less virulent; it takes place through heat, aging, or chemical means
  3. 4. he discovered vaccination
  4. 6. Phagocytosis
  5. 7. alveolar macrophages
  6. 9. theorized that immunization protects people against disease by exposing them to a version of a microbe that is harmless but is just enough like the disease-causing organism, or pathogen, that the immune system learns to fight it
  7. 11. A Russian biologist demonstrated that certain blood cells could ingest foreign material
  8. 12. Largest cells in the peripheral blood
  9. 14. Presence or level of specific antibodies in the blood
  10. 16. Discovered the diphtheria toxin.
  11. 18. frequently lethal state of shock induced by second injection of antigen
  12. 20. peptidoglycan in gram positive bacteria
  13. 21. causative agent of cow pox
  14. 23. the state of being exempted to disease
  15. 24. Discovered complement
  16. 25. lipopolysaccharide in gram negative bacteria.
  17. 26. Can also perform phagocytosis but less efficient than neutrophils (low in number).
  18. 28. Study of immune system
  19. 29. lipoprotein found in mycobacteria.
  20. 31. also called immunoglobulins
  21. 32. Microglial cells
  22. 37. 10 to 15 μm in diameter with a nucleus that has between two and five lobes, which are connected by thin, threadlike filaments