Across
- 2. Thin outer layer of the skin
- 3. Cells found in the skin, lungs, and mucous membranes
- 5. Unknown cause.
- 8. Involves the production of T cells that directly attack or indirectly destroy them
- 10. Containes the nerves, blood vessels, and lympth channels that supply the epidermis
- 11. Most abundant antibodies accounting for 75%-85% of immunoglobulins in plasma
- 12. The initial exposure of the patient to the allergen and the production of allergen-specific IGE
- 17. Cells that are the only T cells that can directly destroy infected cells
- 18. Urticaria of unknown cause with greater than or equal 6 weeks duration
- 20. Found in the deepest layer of the epidermis and produce pigment melanin
- 22. Response that is fast, nonspecific, and no memory
- 23. Key inflammatory mediator
- 25. Swelling that occurs deeper in the skin
- 26. Redness due to surrounding inflammation
- 28. The bodys first line of defense against invaders
Down
- 1. A condition characterized by hives.
- 4. Display the processed antigens on their surface via the MHC molecules
- 6. Antibodies that circulate in the body and bind to foreign substances
- 7. Derived from the Greek word "to eat"
- 9. Itching
- 13. Most common type of white blood cell
- 14. Antibodies that trigger release of histamine from mast cells and basophils
- 15. System is a complex network of specialized cells, tissues, and organs
- 16. The process of ignoring self antigens
- 19. This cell is the central driver of urticaria symptoms
- 21. Activated by the APCS which lead to events that help mount an effective immune response against the antigen
- 24. Response that is slower, specific, and has memory
- 27. Local areas of superficial swelling