Across
- 2. part of the chromosome or chromatid is lost at the next cell division
- 4. the average energy deposited per unit length of track
- 8. a hydroperoxyl radical
- 9. ratio of radiation dose required to cause particular biologic response of cells in oxygen deprived environment to the radiation dose required to cause identical response under normal oxygen conditions
- 10. classic method of displaying the sensitivity of a particular type of cell to radiation
- 11. loss or change of a nitrogenous base in the DNA chain
- 13. chemical unions created between atoms by the single sharing of one or more pairs of electrons
- 16. solitary atoms or most often a combination of atoms that behave as single entities and are very chemically reactive as a result of the presence of unpaired valance electrons
- 18. used to calculate EqD to determine the ability of a dose of any kind of ionizing radiation to cause biologic damage
- 20. results when irradiation occurs early in interphase, before DNA synthesis takes place
- 22. chromosome breakage where the break rejoins in their original configuration
- 23. female and male reproductive cells
- 24. describes the relative capabilities of radiation with differing LETs to produce particular biologic reaction
- 25. a hydrogen radiation and a hydroxyl radical
Down
- 1. the radiosensitivity of cells is directly proportional to their reproductive activity and inversely proportional to their degree of differentiation
- 3. results when irradiation of individual chromatids occurs later in interphase, after DNA synthesis
- 5. injury on the molecular level resulting from exposure to ionizing radiation
- 6. can result when ionizing radiation interacts with DNA and the energy transferred in the process ruptures one of its chemical bonds and severs one of the chain side rails or strands of the ladderlike molecular structure
- 7. programmed cell death
- 12. biologic damage that occurs as a result of ionization of atoms on essential molecules produced by straight interaction with the incident radiation
- 14. the breaking of one or both of the chains of DNA molecule that can be caused by exposure of the molecule to ionizing radiation
- 15. multistage process that first involves the production of reactive free radicals that are created by the interaction of radiation with water molecules
- 17. exposing a cell to as little as 0.01 Gy of ionizing radiation just before it begins to divide can result in the failure of the cell to start dividing on time
- 19. concept that the cell dies if the master or key molecule becomes inactivated as consequence of exposure to ionizing radiation
- 21. branch of biology concerned with effects of ionizing radiation on living systems