Across
- 2. causes premature death
- 3. purine to pyrimidine
- 6. wild type to mutant type
- 7. no change in fitness
- 8. moves the codon reading frame
- 9. one amino acid to a different amino acid
- 12. purine to purine or pyrimidine to pyrimidine
- 13. a sense codon to a stop codon
- 14. removes and replaces a single nucleotide
- 17. removal of the purine base but not the sugar-phosphate backbone
- 18. leaves the chemically modified base in place but undoes the modification
Down
- 1. removes and replaces several nucleotides that distort the shape of the helix
- 4. mutant type to wild type
- 5. causes the appearance of a new trait or function
- 10. a type of mutation where nucleotides are inserted or deleted
- 11. complete or partial loss of protein function
- 15. expressed only under certain conditions
- 16. one codon to a synonymous codon with no amino acid change
