Myo-meter

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Across
  1. 1. Family of transcription factors crucial for muscle development.
  2. 3. This number is simply a calculation of the number of times you have split your cells.
  3. 5. Skeletal muscle progenitors.
  4. 6. Second and final differentiation where muscle progenitors give raise to myotubes.
  5. 8. Process/stage of muscle development characterized by increased contractile activity and organization. Main challenge in the in-vitro muscle field.
  6. 9. Bacterial tissue culture nightmare.
  7. 11. Process involving the organization and alignment of contractile proteins.
  8. 15. Extracellular matrix used in muscle tissue engineering.
  9. 18. Differentiated and immature muscle cell characterized by the expression of Myogenin.
  10. 19. Inhibition of this key signalling molecule promotes muscle progenitor differentiation.
  11. 20. First differentiation where muscle progenitors are derived from iPSCs.
  12. 21. Embryonic structure formed during development, giving rise to skeletal muscle precursor cells and other tissues.
  13. 22. Nutrient-rich solution used to support cell growth and proliferation in tissue culture.
  14. 23. Process to isolate muscle progenitors based on cell surface markers.
Down
  1. 1. Type of mesoderm that gives rise to skeletal muscle progenitors.
  2. 2. Muscle fiber type predominant in fast-twitch muscles.
  3. 4. Antibiotic commonly used with Penicillin that prevents bacterial contamination in cell culture.
  4. 7. Calcium-binding protein located in the sarcoplasmic reticulum of muscle cells, involved in calcium storage and release during muscle contraction.
  5. 10. Early stage of muscle development formed by fusion of skeletal muscle progenitors..
  6. 12. Factors reprogramming adult cells into induced pluripotent stem cells (iPSCs).
  7. 13. Invaginations of the sarcolemma that allow for rapid propagation of action potentials in muscle cells.
  8. 14. Pathway/Signal involved in regulating muscle progenitor proliferation and differentiation.
  9. 16. Component of acetylcholine receptor expressed in mature muscle cells.
  10. 17. Myosin 3 is an _________ marker.