Across
- 1. Family of transcription factors crucial for muscle development.
- 3. This number is simply a calculation of the number of times you have split your cells.
- 5. Skeletal muscle progenitors.
- 6. Second and final differentiation where muscle progenitors give raise to myotubes.
- 8. Process/stage of muscle development characterized by increased contractile activity and organization. Main challenge in the in-vitro muscle field.
- 9. Bacterial tissue culture nightmare.
- 11. Process involving the organization and alignment of contractile proteins.
- 15. Extracellular matrix used in muscle tissue engineering.
- 18. Differentiated and immature muscle cell characterized by the expression of Myogenin.
- 19. Inhibition of this key signalling molecule promotes muscle progenitor differentiation.
- 20. First differentiation where muscle progenitors are derived from iPSCs.
- 21. Embryonic structure formed during development, giving rise to skeletal muscle precursor cells and other tissues.
- 22. Nutrient-rich solution used to support cell growth and proliferation in tissue culture.
- 23. Process to isolate muscle progenitors based on cell surface markers.
Down
- 1. Type of mesoderm that gives rise to skeletal muscle progenitors.
- 2. Muscle fiber type predominant in fast-twitch muscles.
- 4. Antibiotic commonly used with Penicillin that prevents bacterial contamination in cell culture.
- 7. Calcium-binding protein located in the sarcoplasmic reticulum of muscle cells, involved in calcium storage and release during muscle contraction.
- 10. Early stage of muscle development formed by fusion of skeletal muscle progenitors..
- 12. Factors reprogramming adult cells into induced pluripotent stem cells (iPSCs).
- 13. Invaginations of the sarcolemma that allow for rapid propagation of action potentials in muscle cells.
- 14. Pathway/Signal involved in regulating muscle progenitor proliferation and differentiation.
- 16. Component of acetylcholine receptor expressed in mature muscle cells.
- 17. Myosin 3 is an _________ marker.