Across
- 3. wide variation in cell shape
- 8. Benign tumor of adipocytes
- 10. malignant transformation, third step of neoplastic transformation
- 12. growth factor that stimulates fibroblast and increase production of collagen
- 13. ovarian and pancreatic adenocarcinomas spread transcoelomically, resulting in multiple tumor masses throughout the abdomen
- 14. spread Tumor invade through veins to reach the vena cava, commonly sarcomas
- 17. cancerous tumors that invade locally and spread by metastasis
- 19. notable weight loss and debility
- 20. noncancerous tumors that do not invade locally nor spread
- 21. Process of new growth in which normal cells undergo irreversible genetic change
- 22. tissue growth
- 23. antigens embryonic antigens normally not expressed in adult tissue
- 24. abnormal numbers of chromosomes
- 25. poor cell differentiation
Down
- 1. antigens antigens present on both tumor cells and normal cells
- 2. antigens antigens restricted to tumor cells
- 4. development of lymphatic vasculature in tumors
- 5. an irreversible alteration of genetic material, first step of neoplastic transformation
- 6. tumors spread beyond the original host via physical transplantation following direct physical contact between animals of the same species
- 7. extreme variability in nuclear size
- 9. wide variation in cell size
- 11. process by which the immune system identifies and kills microbially infected cells or foreign cells
- 12. outgrowth of initiated cells in response to selective stimuli, second step of neoplastic transformation
- 15. nonneoplastic supporting structures like blood vessels, fibroblast, and inflammatory cells
- 16. tumor consisting of tumor cells termed parenchyma
- 18. Development of new blood vessels
