Neoplasia

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Across
  1. 3. wide variation in cell shape
  2. 8. Benign tumor of adipocytes
  3. 10. malignant transformation, third step of neoplastic transformation
  4. 12. growth factor that stimulates fibroblast and increase production of collagen
  5. 13. ovarian and pancreatic adenocarcinomas spread transcoelomically, resulting in multiple tumor masses throughout the abdomen
  6. 14. spread Tumor invade through veins to reach the vena cava, commonly sarcomas
  7. 17. cancerous tumors that invade locally and spread by metastasis
  8. 19. notable weight loss and debility
  9. 20. noncancerous tumors that do not invade locally nor spread
  10. 21. Process of new growth in which normal cells undergo irreversible genetic change
  11. 22. tissue growth
  12. 23. antigens embryonic antigens normally not expressed in adult tissue
  13. 24. abnormal numbers of chromosomes
  14. 25. poor cell differentiation
Down
  1. 1. antigens antigens present on both tumor cells and normal cells
  2. 2. antigens antigens restricted to tumor cells
  3. 4. development of lymphatic vasculature in tumors
  4. 5. an irreversible alteration of genetic material, first step of neoplastic transformation
  5. 6. tumors spread beyond the original host via physical transplantation following direct physical contact between animals of the same species
  6. 7. extreme variability in nuclear size
  7. 9. wide variation in cell size
  8. 11. process by which the immune system identifies and kills microbially infected cells or foreign cells
  9. 12. outgrowth of initiated cells in response to selective stimuli, second step of neoplastic transformation
  10. 15. nonneoplastic supporting structures like blood vessels, fibroblast, and inflammatory cells
  11. 16. tumor consisting of tumor cells termed parenchyma
  12. 18. Development of new blood vessels