Neoplasia

4. Term that refers to normal mature tissue located in an abnormal location
5. The cellular process directly inhibited by the loss of cadherins in tumor cells during metastasis
8. Assessed by a clinician
10. The term for the extensive fibrous reaction stimulated by tumor cells that increase the production of collagen
11. ____Spread by which tumor cells spread via blood vessels
12. Process by which the immune system identifies and kills microbially infected cells or foreign cells
13. _____antigens are newly expressed molecules on tumor cells
15. Suffix for a malignant epithelial tumor
19. Canine _____ Venereal tumor is an example of what type of tumor
21. Derived from all three embryonic germ layers
23. _____ immunity that is considered to mount the most effective antitumor defenses
25. A nonneoplastic supporting structure of a tumor

1. The development of lymphatic vasculature in tumors
2. The process by which the immune system recognizes and eliminates tumor cells
3. _____antigens are overexpressed self-antigens
6. An example of choristoma
7. Process of “new growth” in which normal cells undergo irreversible genetic changes, which render them unresponsive to ordinary controls on growth exerted from within the “transformed” cell or by surrounding “normal” cells
9. Assessed by a pathologist
14. Embryonic Antigens normally not expressed in adult tissue
16. ____ inflammatory conditions that increase the risk for cancer in affected organs
17. ____Immunotherapy provides the patient with mature effector cells or antibodies that recognize and destroy tumors
18. Mesenchymal tumors originate from this layer
20. In the TNM staging system, what is the indication for no distant metastasis
22. Suffix for a benign mesenchymal tumor
24. this ______ irreversible genetic change in a normal cell