Neoplasia Review

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Across
  1. 4. Syndrome with fibrous skin nodules in German Shepherds
  2. 6. Type of mutation where chromosome arms swap abnormally
  3. 8. Immune cells involved in tumor immunosurveillance
  4. 11. General term for abnormal but non-neoplastic tissue growth
  5. 13. Tumor that arises from bone tissue
  6. 17. Protein that stimulates blood vessel growth (hint: VEGF)
  7. 20. Paraneoplastic condition causing low blood sugar
  8. 22. Process where tumors release substances to weaken the immune system
  9. 24. Loss of cellular differentiation in tumors
  10. 25. Cancer development caused by environmental agents
Down
  1. 1. Process by which tumors enter blood or lymph vessels
  2. 2. Tumor cell movement through the extracellular matrix
  3. 3. Tumor spread across body cavities
  4. 5. Spread of tumors to distant sites
  5. 7. Benign tumor of fat cells
  6. 9. Formation of new blood vessels in tumors
  7. 10. Tumor cells leaving a blood or lymph vessel
  8. 12. Gene family re-expressed in tumors, originally embryonic
  9. 14. Tumor staging system acronym
  10. 15. Blood vessels formed by tumors are often this (not organized)
  11. 16. Mutation type involving insertion or removal of DNA segments
  12. 18. Normal tissue in an abnormal location
  13. 19. Malignant tumor of epithelial origin
  14. 21. Dominant inherited mutation that causes cancer
  15. 23. Tumor suppressor gene known as the "guardian of the genome"