NERVOUS SYSTEM HISTOLOGY CROSSWORD

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Across
  1. 5. Lipid-rich sheath that insulates axons and speeds up electrical conduction.
  2. 8. Connective tissue surrounding individual axons in the peripheral nervous system.
  3. 10. Embryonic cell population that migrates to form much of the PNS and other structures.
  4. 11. Carbohydrate storage granules found in metabolically active cells; appear electron-dense under EM.
  5. 13. CNS immune cells derived from monocytes; perform phagocytosis and respond to injury.
  6. 14. Specialized ectodermal thickening that gives rise to the neural tube.
  7. 16. Growth factor family involved in neuron survival, axon growth, and synaptic plasticity.
  8. 17. Outer dense connective tissue layer that encloses an entire peripheral nerve.
  9. 18. CNS glial cells that form myelin by wrapping around multiple axons.
  10. 20. Connective tissue layer that surrounds a nerve fascicle and contributes to the blood-nerve barrier.
Down
  1. 1. PNS glial cells that myelinate or support peripheral axons, one segment per cell.
  2. 2. Small glial cells in PNS ganglia that surround and regulate the environment of neuronal cell bodies.
  3. 3. Iron-storing pigment seen in tissues after hemorrhage or in conditions of iron overload.
  4. 4. Ciliated epithelial-like glial cells lining the brain ventricles and spinal canal; involved in CSF movement.
  5. 6. Small gaps between adjacent myelin segments that enable saltatory conduction.
  6. 7. Rare adult progenitor cells in CNS niches that can generate neurons and glia.
  7. 9. Embryonic structure formed from the neural plate; gives rise to the brain and spinal cord.
  8. 12. Clumps of rough endoplasmic reticulum found in neuronal cell bodies; stain basophilic.
  9. 15. Star-shaped CNS glia involved in ion balance, neurotransmitter recycling, and the blood-brain barrier.
  10. 19. Brown pigment found in aging neurons and cardiac muscle; a lysosomal digestion by-product.