Neuroendocrinology (Spring 2026)

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Across
  1. 4. Specialized glial-like cells lining the third ventricle, near the median eminence, that regulate molecular exchange between blood, CSF, and the hypothalamus.
  2. 6. Iodine-containing thyroid hormone (T3) that plays a crucial role in metabolism and development.
  3. 8. Cellular process that moves molecules across endothelial barriers via vesicular transport.
  4. 9. Small brain structure that secretes melatonin and regulates circadian timing.
  5. 10. Specialized cells in the nervous system that synthesize and release hormones directly into the bloodstream.
  6. 13. Circulating inactive hormone precursor that must be converted into its active form in peripheral tissues.
  7. 14. DNA regulatory sequence that allows hormone-receptor complexes to modulate gene transcription, hormone response ________.
  8. 15. Releasing and inhibiting hormones secreted by the neurosecretory cells of the hypothalamus make their way to the anterior pituitary via the _____ portal system.
Down
  1. 1. Cells embedded in the brain capillary basement membrane that regulate blood–brain barrier stability and permeability.
  2. 2. Temporary adaptive shift away from normal physiological set points during stress or threat.
  3. 3. Referring to the nervous system division that independently regulates gastrointestinal function.
  4. 5. Specialized brain regions or organs lacking a typical blood–brain barrier that detect circulating signals and regulate homeostasis.
  5. 7. Sensory process that monitors internal bodily states such as temperature, osmolarity, and energy balance.
  6. 11. A hormone released by the posterior pituitary that enables maternal behavior.
  7. 12. Glial cells whose endfeet contribute structurally and functionally to the blood–brain barrier.