Neurotransmission

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Across
  1. 2. Grassy mound on a map, or the decisive axonal cone where graded waves must clear the threshold to fire.
  2. 4. Node-to-node jumping conduction named after the Latin verb 'to leap'.
  3. 7. Toadstool-named GPCR family: odd subtypes rally IP3/DAG while even subtypes dampen cAMP.
  4. 8. Rest-and-digest division stretching long preganglionic cables out to ganglia buried in the target organ.
  5. 11. Outgoing motor nerve highway carrying orders from the central processor out to the periphery.
  6. 13. Aldous Huxley's fictional narcotic, or the nucleated cell body where a neuron handles its housekeeping.
  7. 14. Self-governing meshwork of gut neurons that runs peristalsis without waiting for brain permission.
  8. 15. Tree-branched neuronal listeners that gather incoming synaptic whispers and funnel them toward the soma.
  9. 16. Handcuff-sounding beta protein recruited after GRK tags a receptor tail, dragging it into a coated pit.
  10. 20. Voluntary peripheral division that sprints straight from spinal cord to skeletal muscle without a ganglion stop.
  11. 21. Calculated the equilibrium voltage for a single ion species, before Goldman invited the neighbours.
  12. 22. All-or-nothing binary clock style exemplified by an axonal action potential.
  13. 23. Continuous, variable-amplitude clock style exemplified by graded potentials and synaptic cleft release.
Down
  1. 1. Lightning-fast synaptic cleft janitor that hydrolyzes acetylcholine back into choline and acetate.
  2. 3. Rate-limiting cytosolic enzyme on tyrosine—or the vesicular enzyme that turns dopamine into noradrenaline.
  3. 5. Sensory nerve highway arriving at central command; swap the first vowel for an E and you are leaving.
  4. 6. Overshooting below resting potential while sluggish potassium gates take their time closing.
  5. 9. Greasy Schwann-built insulation jacket whose patchy autoimmune loss causes multiple sclerosis.
  6. 10. Dietary nutrient carried into the nerve terminal with sodium to have a cytoplasmic ChAT with acetyl-CoA.
  7. 12. Positive-bound voltage swing sparked when voltage-gated sodium channels fling open before potassium lags behind.
  8. 17. Bare uninsulated gaps along a myelinated axon where the action potential leaps to save time.
  9. 18. Pentameric ion channel that demands two acetylcholine molecules at once to let sodium and potassium rush in.
  10. 19. Gilded physiologist who added chloride and multiple cations to turn a one-ion voltage formula realistic.
  11. 20. Fight-or-flight division with short preganglionic stubs near the spine and long noradrenergic reach.
  12. 24. Final Greek character momentarily traced by a fusing synaptic vesicle as it empties into the cleft.