nonspecific defense

2. a phagocytic cell constituting the largest group of circulating granulocytes
4. IL-12 stimulates NK cells to secrete IFN-?
10. Lipid inflammatory mediators produced by mast cells are important mediators of allergic reactions
12. an enzyme that catalyzes the breakdown of the complement protein C3 into two components C3a and C3b
13. a cytokine secreted by cells infected with viruses
15. cytokines that stimulate lymphocyte movement and regulate their migration from blood to tissues
17. the process that a cell undergoes after the complement system is activated at a late stage
19. the process by which macrophages and neutrophils surround (engulf) large particles (e.g. microorganisms)
20. cells containing numerous granules, reside in most tissues near blood vessels and have a receptor for IgE

1. cytosolic complex of NLRP-3, adaptor protein, and caspase-1, responsible for the production of proinflammatory cytokines
3. Acronym for pathogen-associated molecular pattern
5. created by the fusion of a phagosome with a lysosome
6. NK cells (Natural Killers) release perforins and granzymes as a result of fusion with the cell membrane of the target cell. We say that these are cells distinguished by natural.....
7. granulocytes that participate in the process of neutralization of extracellular parasites and in allergic diseases
8. molecules (antibodies, complement proteins) that can attach to the surface of a pathogen and thereby facilitate phagocytosis by phagocytic cells
9. cytokines, participate in the communication process between cells of the immune system
11. a cell present in tissues that arises from a blood monocyte. When activated, it phagocytizes and kills microorganisms
14. tissue reaction in which mediators migrate to sites of infection and tissue damage
16. one of the complement activation pathways, triggered by antibodies bound to antigens on the surface of microorganisms
18. adhesion molecules (with lectin properties) mediating the rolling of blood neutrophils on the endothelium