nonspecific defense

1. cytosolic complex of NLRP-3, adaptor protein, and caspase-1, responsible for the production of proinflammatory cytokines
4. cytokines that stimulate lymphocyte movement and regulate their migration from blood to tissues
6. cytokines, participate in the communication process between cells of the immune system
7. granulocytes that participate in the process of neutralization of extracellular parasites and in allergic diseases
9. one of the complement activation pathways, triggered by antibodies bound to antigens on the surface of microorganisms
12. IL-12 stimulates NK cells to secrete IFN-?
13. created by the fusion of a phagosome with a lysosome
16. an enzyme that catalyzes the breakdown of the complement protein C3 into two components C3a and C3b
18. Acronym for pathogen-associated molecular pattern
19. adhesion molecules (with lectin properties) mediating the rolling of blood neutrophils on the endothelium
20. Lipid inflammatory mediators produced by mast cells are important mediators of allergic reactions

2. the process that a cell undergoes after the complement system is activated at a late stage
3. a cell present in tissues that arises from a blood monocyte. When activated, it phagocytizes and kills microorganisms
5. tissue reaction in which mediators migrate to sites of infection and tissue damage
8. a cytokine secreted by cells infected with viruses
10. cells containing numerous granules, reside in most tissues near blood vessels and have a receptor for IgE
11. NK cells (Natural Killers) release perforins and granzymes as a result of fusion with the cell membrane of the target cell. We say that these are cells distinguished by natural.....
14. the process by which macrophages and neutrophils surround (engulf) large particles (e.g. microorganisms)
15. a phagocytic cell constituting the largest group of circulating granulocytes
17. molecules (antibodies, complement proteins) that can attach to the surface of a pathogen and thereby facilitate phagocytosis by phagocytic cells