Oncology & Immunology Crossword: 27 Feb 2026

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Across
  1. 4. Common abbreviation for squamous cell carcinoma.
  2. 6. Common skin side effect seen with EGFR or checkpoint inhibitors.
  3. 14. Autoimmune hair-loss disorder often treated with JAK inhibitors.
  4. 15. Term for treatments applied directly to the skin.
  5. 16. Lymphoma considered the nodal counterpart of CLL.
  6. 17. PD-1 inhibitor approved for advanced cutaneous squamous cell carcinoma.
  7. 19. Common abbreviation for basal cell carcinoma.
  8. 21. Therapy given before surgery to shrink or downstage a tumor.
  9. 22. Abbreviation for eosinophilic esophagitis.
  10. 23. Therapy given after surgery to lower the risk of cancer coming back.
  11. 26. Field of medicine focused on cancer.
  12. 28. Type of engineered antibody that can bind two different targets at once.
  13. 30. Study in which new treatments are tested.
Down
  1. 1. Classic endocrine therapy for hormone receptor–positive early breast cancer.
  2. 2. Term for therapies that act throughout the body.
  3. 3. Medical term for itching.
  4. 5. Kinase family targeted by baricitinib and other alopecia treatments.
  5. 7. Acid-reducing drug class that blocks histamine receptors in the stomach.
  6. 8. Short form for a doctor who specializes in skin.
  7. 9. Numbered stage of a clinical trial.
  8. 10. Antibody that blocks IL-4 and IL-13 in atopic dermatitis and eosinophilic esophagitis.
  9. 11. Local therapy that may follow surgery in certain high-risk cancers.
  10. 12. Umbrella term for basal and squamous cell carcinomas of the skin.
  11. 13. Description for breast cancer found before distant spread.
  12. 18. Common abbreviation for proton pump inhibitor.
  13. 20. B-cell and T-cell targets paired in some bispecific antibody designs.
  14. 24. General term for adverse effects from therapy.
  15. 25. Indolent leukemia often treated with BTK inhibitors and antibodies.
  16. 27. Receptor overexpressed in a specific targeted subtype of breast cancer.
  17. 29. Main local treatment for many early skin and breast cancers.