Outline the pathological changes in blood vessels in both large and small vessel peripheral arterial disease

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Across
  1. 3. Black, mummified tissue from severe arterial insufficiency
  2. 8. Oxygen deprivation at the tissue level
  3. 10. Stiffening of the large and middle arteries
  4. 11. Death of tissue due to prolonged ischemia
  5. 13. The ability of an artery to expand or contract
  6. 15. Platelet-rich clot forming on atherosclerotic plaque
  7. 16. Inflammatory cells filled with lipid in plaques
  8. 17. Complete blockage of the arterial lumen
  9. 18. A hollow, central channel through which the blood flows through
Down
  1. 1. A chronic condition involving glucose control that affects the blood vessels
  2. 2. Mechanism of arterolosclerosis
  3. 4. Mechanism of arteriosclerosis
  4. 5. The buildup of calcium deposits in the artery walls
  5. 6. High bloodpressure
  6. 7. Reduced blood flow to the peripheral tissue
  7. 9. Stiffening of the small arteries and arterioles
  8. 12. Replacement of normal tissue with scar tissue
  9. 14. A slow buildup of fatty substances on the artery wall