Across
- 2. Peptide that promotes inflammation and directly stimulates nociceptors
- 5. Tree-like extensions that receive incoming signals from other neurons
- 6. Neurotransmitter linking emotional states to the experience of discomfort
- 10. Catecholamine that attenuates nociceptive transmission via alpha-2 adrenergic receptors
- 11. A sufficiently strong environmental change that initiates an electrical response in a neuron
- 12. An enzyme that hydrolyses acetylcholine, terminating its action at the synapse
- 14. A neurotransmitter that activates muscle fibres at the neuromuscular junction and is broken down by acetylcholinesterase
- 15. Specialized cell in the eye that converts light energy into an electrical signal
- 17. Intervention or substance that reduces or eliminates the perception of discomfort
- 19. A long projection that conducts electrical impulses away from the soma toward target cells
- 20. Monoamine that modulates spinal processing of discomfort from brain centres
Down
- 1. Conversion of a harmful stimulus into electrical activity by peripheral sensory receptors
- 3. Adjustment in signal strength within the spinal pathways, often via inhibitory substances such as endogenous opioids
- 4. Glial cell in the central nervous system that extends processes to myelinate multiple axons
- 7. Neuron located within the central nervous system that links sensory input to motor output
- 8. Excitatory amino acid that rapidly activates receptors during acute nociceptive signalling
- 9. A junction where presynaptic terminal releases chemicals that influence a postsynaptic membrane
- 13. The sequential activation of adjacent membrane segments, allowing the impulse to travel along the axon
- 16. Inflammatory mediator that contributes to swelling and sensitization of sensory endings
- 18. Endogenous opioids that suppress signal transmission and produce a calming effect