Patho Assessment 1 Immunity and Inflammation

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Across
  1. 4. involves an increase in capillary permeability that occurs 4 to 24 hours after injury
  2. 7. associated with foreign bodies (splinters, sutures, silica, asbestos) or microorganisms (TB, Syphilis, Deep fungal infections)
  3. 10. nonspecific immunity; the natural resistance with which a person is born
  4. 13. reflects the site of infection
  5. 14. Contain pus; composed of degraded whit blood cells, proteins and tissue debris
  6. 15. bone marrow and thymus; provide the environment for immune cell production and maturation
  7. 16. heat
  8. 19. found in the blood and is essential for the activity of antibodies; activation of this increases bacterial aggregation rendering them more susceptible to phagocytosis
  9. 20. immune cells; accomplish the final stages of the immune response with the elimination of the antigen; activated T lymphocytes, mononuclear phagocytes, and other leucocytes function as effector cells in different immune responses
  10. 21. substances foreign to the host that can stimulate an immune response
  11. 27. Occurs with more serious injury and continues for several days and damages the vessels in the area
  12. 30. cell mediated immunity; memory
  13. 32. collective, coordinated response of the cells and molecules of the immune system
  14. 33. small, clean wound
  15. 35. may require lab testing to detect (hepatitis or increased WBC count)
  16. 36. specific protection induced following exposure to antigens
  17. 37. fibrous structural proteins, water-hydrated gels that permit resilience and lubrication, adhesive glycoproteins that connect the matrix elements to each other and to cells
  18. 41. predictable patterns (chickenpox, measles)
  19. 42. stimulate the growth and differentiation of bone marrow progenitors of immune cells
  20. 43. cytokines that stimulate the migration and activation of immune and inflammatory cells
  21. 44. binds to mast cells and basophils; involved in parasitic infections, allergic and hypersensitivity reactions
  22. 46. forms atural antibodies; prominent in early immune response; activates complement
  23. 47. Occurs with minor injury
  24. 49. function to trap and process antigen and promotes its interaction with mature immune cells
Down
  1. 1. infiltration of neutrophils, exudate - self limited and short duration
  2. 2. infiltration by mononuclear cells (macrophages) and lymphocytes, proliferation of fibroblasts - self perpetuating and may last weeks, months, or years
  3. 3. displays antiviral, antitoxin and antibacterial properties; responsible for protection of newborn; activates complement and binds to macrophages
  4. 5. pain
  5. 6. recognize antigens; receptors on immune cells, secreted proteins
  6. 8. immune cells; assist in orchestrating and controlling the immune response
  7. 9. contain large amounts of fibrinogen and form a thick and sticky meshwork
  8. 11. soluble proteins secreted by cells of both the innate and adaptive immunity
  9. 12. great loss of tissue with contamination
  10. 16. pathogen specific antibodies given to the patient as an infustion to facilitate neuralization, phagocytosis, and clearance of infectious agents above and beyond the capabilities of the host
  11. 17. mediated by molecules in the blood; principle defense against extracellular microbes and toxins
  12. 18. present processed antigenic fragments to CD4 T cells; necessary for effective interaction among immune cells
  13. 19. present processed antigen to cytotoxic CD8 T cells; restrict cytolysis to virus infected cells, tumor cells, transplanted cells
  14. 22. can be shared by a number of diverse infectious diseases (s+s like fever, myalgia, headache)
  15. 23. swelling
  16. 24. humoral immunity; memory
  17. 25. Develop on mucous membrane surfaces, are composed of necrotic cells enmeshed in a fibropurulent exudate
  18. 26. supplementing or stimulating the host's immune response so that the spread of a pathogen is limited or reversed
  19. 28. Present in the spaces between cells and the connective tissue and between the epithelium and supporting cells of blood vessels
  20. 29. specific protection induced through transfer of protective antobodies against an antigen; transferred from another source (ie igg crosses placenta to new born, iga in colostrum)
  21. 31. surrounds epithelial, endothelial, and smooth muscle cells
  22. 34. mediated by specific T lymphocytes; defends against intracellular microbes such as viruses
  23. 38. specific immunity; the second line of defense, responding less rapidly, but more effectively
  24. 39. found on B lymphocytes; needed for maturation of B cells
  25. 40. loss of function
  26. 45. predominant ig in body secretions; protects mucous membranes
  27. 48. redness