Across
- 3. suppresses the production of IL-2, interferon gamma, and other cytokines; most effective immunosuppressants available
- 7. decrease bone density, hot flashes, decreased libido, erectile dysfunction, gynecomastia, dysrhythmias, pulmonary edema
- 8. synthetic erythropoetin, stimulates bone marrow to produce RBCs, used in chronic kidney disease and chemo
- 10. also known as Neupogen, glycoproteins that promote the production of WBCs
- 11. attacks tumors at the cellular level by interrupting processes or inhibiting substances necessary for cellular replication and life
- 12. also known as Nolvadex, SERM that stops growth of breast cancer cells which are estrogen dependent cancers
- 13. suppresses the immune system by interfering with cellular DNA synthesis, folic acid analog- taking folic acid decreases its effectiveness, taken on empty stomach
- 14. medications that stimulate cells in the body to increase production
Down
- 1. used to treat cancer, RA, MS, post-transplant and other inflammatory conditions
- 2. first created and most used calcineurin inhibitor, suppresses production of IL-2, interferon gamma, and other cytokines to treat autoimmune disorders
- 4. contain antibodies directed at specific antigen, passive immunity, ex- Hep B, RhoGAM, Rabies, Tetanus
- 5. drugs that decrease or prevent an immune response, treats rejection of organs, and other autoimmune illnesses, leads to increased susceptibility to infection
- 6. endometrial cancer, hypercalcemia, N/V, thromboembolic events, DVT, PE, CVA, Hot flashes, vaginal discharge/bleeding
- 9. also known as Lupron, used to treat prostate cancer