pharmacodynamics115

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Across
  1. 6. An example of a drug that acts on ion channels is?
  2. 8. Ligands typically recognise and bind to?
  3. 10. The ability to produce an effect on a particular target tissue
  4. 12. Relates to the mechanism of action of medicines
  5. 13. An example of an allosteric modulator is a class of drugs called?
  6. 16. Drug that attaches to a receptor, but does not initiate an action
Down
  1. 1. This term refers more specifically to a decrease in the response of the receptor–second messenger system and is a common feature of many receptors, it is?
  2. 2. Drug A is administered to a person that acts on a particular receptor. Unfortunately, it is given in overdose. Drug B is then administered, which blocks that receptor. The effects of drug B result in a reduction of the effect of drug A. Drug A is acting how?
  3. 3. the ability of a drug to achieve the desired therapeutic effect
  4. 4. A drug that activates a receptor
  5. 5. Enzymes typically act as catalysts to facilitate the conversion of what into products
  6. 7. Most drugs display preference for one subtype of receptor over others this is referred to as?
  7. 9. This term is used clinically to describe diminished responsiveness after repeated exposure to the same concentration of the drug
  8. 11. the amount of drug required to produce 50% of that drug's maximal effect; the more potent the drug, the lower the dose required for a given effect.
  9. 14. On the dose-response curve the concentration at which the effect is 50% of the maximum is called the
  10. 15. The strength of the binding interaction between a drug and its molecular target is defined as?
  11. 17. An abbreviation for Transporters that facilitate active transport across a membrane and that contain a distinct ATP binding site are called