Across
- 7. Protein molecule which a chemical/drug binds to
- 8. Enzymes that catalyse many oxidation reactions
- 10. Circulation of drugs through the bile and intestine
- 14. A substance which occurs naturally in the body
- 15. A substance that increases the velocity of a chemical reaction
- 16. How the body interacts with a drug i.e. how the drug is absorbed, distributed, metabolised and excreted
- 18. Drug that binds to the receptor of a cell and blocks an action.
- 19. Describing how strongly a drug binds to a receptor.
- 20. Dissociation of a substance in solution into ions (charged particles)
- 21. Phase I reaction. Substance is combined with oxygen, or hydrogen atoms are removed. Overall increased positive charge.
Down
- 1. Product of metabolism
- 2. Indicates the ability of a drug to produce a response
- 3. Drug that binds to a receptor of a cell and triggers a response by the cell
- 4. Phase I reaction. The addition of hydrogen atoms; gain of electrons. Overall increased negative charge.
- 5. The study of actions of drugs on the body
- 6. Act or process of elimination of waste matter
- 9. Physical and chemical processes by which living organism is made up (anabolism) and by which large molecules are broken down into smaller molecules (catabolism).
- 11. A substance which comes from outside of the body
- 12. Readily absorbing moisture. Strong polar groups that readily interact with water. ‘Water loving’
- 13. substances that become ions in solution and acquire the capacity to conduct electricity
- 17. Phase II reaction. The joining of a toxic substance with a natural substance of the body to form a detoxified product for elimination from the body