Pharmacology (General and Local Anesthetics)

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Across
  1. 7. An increase in cardiac output and pulmonary blood flow will ________ uptake of anesthetic into the blood
  2. 9. Brand name of tetracaine
  3. 11. A partially water soluble and ligth lipid soluble phencyclidine derivative
  4. 13. It's pronounced lipophilicity has relegated its application to topical anethesia
  5. 14. Is an alkyl phenol with hypnotic properties that is chemically distinct from other groups of intravenous anesthetics
  6. 15. Is largely restricted to topical anesthesia for ear,nose and throat procedures, where its intense vasoconstriction can serve to reduce bleeding
  7. 16. Has the highest clearance of amino-amide anesthetic s
  8. 17. Circulating anesthetic also demonstrate _____________ effects having an impact on coagulation platelet aggregation and microcirculation
  9. 18. Brand name of fospropofol
  10. 19. Are unique among the group of intravenous anesthetics in that their action can readily be terminated by administration of their selective antagonist, flumazenil
  11. 21. Has limited application due to its poor block characteristics
  12. 23. Applied to mixtures in which the combination of elements has lower meting temp. than its component elements
  13. 27. The primary mechanism of local anesthetics is blockade of voltage-gated _______ channel
  14. 28. Is an S(-) enantiomer in a homologous series that includes bupivacaine and mepivacaine
  15. 29. Brand name of desflurane
Down
  1. 1. Brand name of prilocaine
  2. 2. Had an excellent record as an intermediate duration anesthetic
  3. 3. Is likely to be associated with a decrease in cerebral blood flow without significant changes in ICP and CMRO2
  4. 4. Brand name of articaine
  5. 5. Use as an epidural agent in obstetrical anesthesia where its rapid hydrolysis served to minimize risk of systemic toxicity or fetal exposure
  6. 6. Brand name of ketamine
  7. 8. Brand name of levobupivacaine
  8. 10. The Stage I in Guedel's signs
  9. 12. Causes adrenocortical suppression by producing a dose dependent inhibition of 11 beta-hydroxylase
  10. 19. Is a biologic toxins that bind to receptors within the channel and prevent inactivation
  11. 20. The anesthetic state is achieved when the partial pressure of the anesthetic in the brain reaches a threshold concentration determine by its
  12. 22. Used primarily for spinal anesthesia
  13. 24. The easiest anesthetic end point to measure
  14. 25. Increase heart rate because they cause less depression of baroreceptor reflex
  15. 26. Brand name of procaine