Across
- 4. non-selective beta-blockers should not be used with this condition
- 5. type of adrenergic receptor found on smooth muscle membranes of arteries
- 6. used for treatment of spasticity
- 7. type of solubility that allows crossing of blood-brain barrier
- 11. study of the processes of drug absorption, distribution, metabolism, excretion
- 12. neurotransmitter released at the autonomic ganglion
- 13. decreased drug effects after chronic use
- 16. is converted into norepinephrine
- 17. location of first-pass metabolism
- 18. neurotransmitter released by adrenal medulla
- 19. beta-blockers have this impact on heart rate
- 20. alpha-blocking drugs relax smooth muscle here to improve urinary flow
- 21. most lipid-soluble beta-blocker
- 22. drug administration that does not involve GI tract
- 23. interferes with the synthesis of norepinephrine
Down
- 1. type of muscle relaxed by epinephrine
- 2. sympathetic effect on arteries to cardiac and skeletal muscle
- 3. cholinergic drugs are used for this condition
- 8. ACH receptor on cell membranes of viscera
- 9. diverts blood from organs not involved in fight or flight
- 10. controlled drugs are assigned to one of five
- 14. type of receptor at the postganglionic neuron
- 15. nerves commonly referred to as autonomic nervous system
- 19. a direct-acting skeletal muscle relaxant
- 24. main clinical use of beta-blockers is to decrease activity here