Pharmacology Terminology

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Across
  1. 4. block agonist by binding to an allosteric site
  2. 6. The study of substances that interact with living systems through chemical processes
  3. 13. any molecule that binds to a receptor
  4. 14. A naturally occurring poisonous substance that is produced within living cells or organisms (e.g. tetrodotoxin)
  5. 16. Synthetic poisons (e.g. glycophosphate in herbicide)
  6. 19. increase the response of a receptor
  7. 21. Inhibition of an agonist’s action downstream of the receptor
  8. 23. decrease the response of a receptor
  9. 24. Neutralization of an agonist through physical complexation
  10. 25. A chemical substance used in the treatment, cure, prevention, or diagnosis of disease or used to otherwise enhance physical or mental well-being
  11. 26. Chemical substances that cause harm to organisms when sufficient quantities are absorbed, inhaled, or ingested
  12. 27. A ligand that binds to a different site from the endogenous ligand
  13. 28. Competitive or Non-competitive inhibition at receptor target
Down
  1. 1. A ligand that binds to the same site as an endogenous signaling molecule
  2. 2. A group of substances that bind to a receptor to change the response to stimuli
  3. 3. Medical science concerned with disease caused by or uniquely associated with toxic substances
  4. 5. compete for the binding site with ligand to block agonist
  5. 7. Protein that recognizes a signaling molecular endogenous to the organism and translates that recognition into a meaningful cellular event
  6. 8. Provide a full response for a population of receptors
  7. 9. Impediment to absorption or distribution, or the enhancement of elimination of a drug
  8. 10. Science involving usage of substances to prevent, diagnose, or treat disease
  9. 11. Desired physiological or behavioral changes produced by the drug
  10. 12. capacity of ligand to activate a receptor
  11. 15. Amount of drug in the circulation that is free to bind at target sites
  12. 17. Interaction of drug with target receptors, cells, tissues
  13. 18. Produce a sub-maximal response despite fully occupying population of receptors
  14. 20. Property of a ligand to block the action of an agonist
  15. 22. The study of adverse effects of substances on living systems