Prophylaxis of Stroke in AF

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Across
  1. 5. the SPAF-1 trail showedthe annual rate of stroke was similar for patients with paroxysmal and _____ AF
  2. 6. necessary for blood clotting
  3. 7. prevents prothrombin from being converted to thrombin
  4. 8. branded generic warfarin
  5. 9. primary composite endpoints of competitor trials
  6. 10. not a US AF triai
  7. 11. head and shoulders above other safeties
  8. 13. dabigatran is a substrate of this
  9. 14. indicated for AF with embolization but used primarily when oral anticoag must be interrupted for surgery
Down
  1. 1. pt measure the activity of this pathway
  2. 2. a measure of renal function
  3. 3. 2c9 is part of this enzyme superhighway
  4. 4. increased pressure in a confined anatomic space adversely affecting circulation
  5. 5. in the common pathway and includes factor I, II and fibrin among others
  6. 12. can be adminsitered instead of warfarin in low risk AF patients
  7. 13. pradaxa is an oral _____