Proteins OCAT

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Across
  1. 2. A special type of covalent linkage with partial double-bond character
  2. 4. This antibiotic works by inhibiting the 30S prokaryotic ribosomal subunit
  3. 7. What city in South Africa was Isaac born in?
  4. 8. What is one of Eric's favourite hobbies? (Hint: Cessna)
  5. 10. This type of protein processing takes MUCH longer than the other (e.g. bacterial)due to the number of post-translational modifications
  6. 14. Area of the endoplasmic reticulum in which lipid synthesis occurs
  7. 15. Organelle system that includes the Golgi apparatus, smooth and rough ER, and lysosomes
  8. 17. Where are the best bougie tacos in Hamilton? (Two words, no space)
  9. 18. this is the eukaryotic ribosome TOTAL size in Svedbergs
  10. 19. A first-year healthsci class in which the teacher says "......................." (nothing)
  11. 20. This type of structure arises when the four subunits of hemoglobin interact to form a complex
  12. 21. I am a mature polypeptide; I've been processed
  13. 24. Protein structure that is determined by hydrogen bonding between the N-C-C backbone of a polypeptide chain
  14. 25. Best member of the Beatles according to Isaac
  15. 27. Where is the best all-you-can-eat sushi in Hamilton?
  16. 31. Protein structure that is determined largely by hydrophobic interactions between functional groups on the amino acids in a polypeptide chain; this gives rise to noticeable 3D structure
  17. 32. What is Chari's favourite course in a 3-course meal?
  18. 35. Addition of a sugar group to a polypeptide
  19. 37. Organelle in which polypeptide/protein tagging and shipment occurs
  20. 38. Protein structure that is solely determined by the sequence of amino acids in the chain
  21. 39. A special amino acid that is only recruited under cellular conditions of high concentrations of selenium
Down
  1. 1. Where can you find the best and most reasonably priced burrito bowl on campus? (Available with meat or tofu or beans)
  2. 2. What do you call a chain of 3 or more amino acids?
  3. 3. A method of identifying proteins in a histological sample with similar techniques to immunoblotting (used to identify anatomical pathologies)
  4. 5. A type of active transporter (a protein) found in cell membrane that can "pump" out substances; expression of these proteins is found as an antibacterial resistance mechanism
  5. 6. Property of some (20) amino acids in that they can be used, in sequence, to produce proteins
  6. 9. What is the best flavour of non-dairy milk?
  7. 11. A three letter code that "tells" the ribosome which tRNA to recruit
  8. 12. A former prime minister of India (last name Gandhi) whose eye exam (at the optometrist) Chari accidentally interrupted
  9. 13. Proteins in the cytosol that can be recruited to refold (and fix) misfolded proteins
  10. 16. This type of immunoblotting is used to identify specific proteins in a sample! (We will go over all of these in lots more detail later btw, don't worry!)
  11. 22. Area of the endoplasmic reticulum in which protein synthesis and folding primarily take places
  12. 23. Controlled/programmed cell death
  13. 26. Protein structure that arises from interactions between SEPARATE polypeptide chains
  14. 28. A type of acid comprised of an N-C-C structure that is used to make peptides
  15. 29. A type of NORMAL structural protein that can mutate to induce the misfolding (and thus dysfunction) of other proteins of its same type
  16. 30. acronym for cellular event that arises when misfolded proteins are detected in the endoplasmic reticulum
  17. 33. A method of identifying proteins in a sample that does NOT use a polyacrylamide/agarose gel like in immunoblotting
  18. 34. A mechanism of speeding up the type of translation that takes a relatively long time
  19. 36. Type of polypeptide maturation and processing that is currently hypothesized to occur in the Golgi apparatus