Psoriatic Arthritis

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Across
  1. 3. ‘Largest’ environmental risk factor for PsA?
  2. 5. The main resident cells in the synovium
  3. 7. Anti-IL23 biologic
  4. 8. These cells build more bone in PsA
  5. 11. A T cell therapy licenced in 2016 by the EMA for PsA “abatacept”
  6. 12. Email traps the small molecular inhibitor, strangely
  7. 13. North of England city provides a score for 15 down
  8. 18. Relating to PsO, the HR for PsA is highest when this area is involved
  9. 19. These proteases are important in matrix degradation and involve a metal
Down
  1. 1. Heinrich _______, described this phenomenon; when deep it may cause PsA
  2. 2. This condition is thought to be a feature of PsA circa 50% of cases, but has a prevalence of only 5% of controls
  3. 4. Prevalence of HLA B27 in Ireland (%)
  4. 6. Sausage Toe
  5. 9. Bug bear-ing psoriasis?
  6. 10. A disease activity score for PsA, initially
  7. 14. A surgical cure for psoriasis?
  8. 15. Inflammation where bone meets tendon
  9. 16. Erosive, disco-vertebral lesion
  10. 17. This ocular pathology occurs in 7% of PsA patients