Pulmonary and Systemic Delivery

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Across
  1. 3. belongs to the peptide class and is used for diabetes mellitus
  2. 4. the regions with less or no mucus offer the lease resistance to the absorption of
  3. 7. what are the three parts of the ear: external, middle and
  4. 8. what is clear,translucent tissue and is supplied with oxygen and other nutrients by lacrimal fluid
  5. 12. these factors can profoundly affect the disposition of inhaled aerosols in the lungs
  6. 13. this drug is used for asthma and COPD and is a corticosteroid
  7. 15. volume volume of air inhaled in a single breath
  8. 16. this drug is also used for asthma and COPD
  9. 17. receive the entire cardiac output and are the best perfused organ in the body
  10. 18. in tidal volume generally leads to deposition of the aerosolized particles in the distal tracheobronchial region including the alveolar region
Down
  1. 1. is present in most of the respiratory tract except in the alveolar region
  2. 2. pulmonary drug delivery is directly related to respiratory structure and
  3. 5. the presence of mucus and pulmonary what affects pulmonary drug absorption
  4. 6. how inhaled insulin is believed to be transported across the alveolar cells
  5. 9. the conducting airways consist of the trachea, bronchioles, and
  6. 10. the respiratory region consists of three regions: nasopharnyx, tracheibrachial pulmonary region
  7. 11. this route is attractive for frug delivery because it offers large surface area for drug absorption
  8. 14. is divided into two main segments