Colorectal cancer and purine metabolism

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Across
  1. 3. Are produced during hypoxanthine degradation by xanthine oxidase
  2. 5. pathway of purine metabolism that happened under normal physiological condition
  3. 7. Has high affinity to transport hypoxanthine
  4. 11. Irreversible pathway
Down
  1. 1. Is the second leading cancer in the world
  2. 2. purine metabolism pathway that happened under the cellular conditions
  3. 4. Bidirectional transporter family
  4. 6. the end product of purine metabolism
  5. 8. The building blocks for DNA and RNA
  6. 9. One of purine exogenous sources
  7. 10. can be recycled again to form inosine monophosphate