RBC Morphological Alterations

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Across
  1. 2. RBC abnormality that occurs as a result of fragmentation/mechanical injury. Resemble RBC "shreds"
  2. 4. Name of morphological alteration with irregular, spiculated red blood cell membrane
  3. 6. Toxicosis in dogs and cats that can result in the formation of Heinz Bodies and Eccentrocytes; found in post-1982 pennies
  4. 9. RBC abnormality that is normal in cats and horses
  5. 11. Condition in cats that results in the manifestation of elliptocytes in peripheral circulation
  6. 13. Dog breed in which you could see non-pathologic macrocytosis without an accompanying polychromasia
  7. 14. Toxicosis in sheep that can result in the formation of Heinz Bodies and Eccentrocytes
  8. 16. Disease of cats in which you could see a macrocytosis without an accompanying polychromasia
  9. 17. RBC abnormality that should be distinguished from rouleaux, primarily associated with IMHA
  10. 18. Diseases of this organ can result in poikilocytosis in cats
  11. 20. Term used to describe an increase in MCV
  12. 22. RBC abnormality that has an increased surface to volume ratio and is naturally resistant to osmotic lysis
Down
  1. 1. RBC abnormality associated with increased membrane permeability. Most significantly seen in Alaskan Malamutes
  2. 3. Solution that can be applied to a peripheral blood smear to distinguish between rouleaux and agglutination
  3. 5. Mineral that plays an essential role in iron transfer and absorption. Deficiencies can result in an iron deficiency
  4. 7. Groups within red blood cells that are altered during oxidative injuries, resulting in the formation of Heinz Bodies and Eccentrocytes
  5. 8. Toxicity in horses that can result in the formation of Heinz Bodies and Eccentrocytes
  6. 10. The most common cause of microcytosis involves ________ deficiency
  7. 12. RBC morphological alteration expected to be seen in a peripheral blood smear of an animal with extravascular hemolysis
  8. 15. Can potentially arise from artifactual mechanisms, such as excess EDTA relative to sample volume and aged blood with ATP depletion
  9. 19. This vitamin acts as a cofactor in heme synthesis. When deficient, can result in an iron deficiency
  10. 21. Species in which you will most likely observe inconsequential drepanocytes (sickle cells)