Across
- 1. The exchange of oxygen and carbon dioxide between the alveoli and the blood in pulmonary capillaries.
- 4. A molecule released by red blood cells during glucose breakdown that binds to hemoglobin and decreases its affinity for oxygen, promoting oxygen unloading to tissues.
- 5. Hemoglobin that is bound to carbon dioxide via its globin portion, accounting for about 23% of CO2 transport in the blood.
- 12. A group of neurons in the anterior medulla that fire spontaneously to initiate quiet inspiration and coordinate breathing rhythms.
- 13. The effect of pH on the oxygen-hemoglobin dissociation curve; decreased pH (more H+ ions) reduces hemoglobin's affinity for oxygen, promoting unloading of oxygen to tissues.
- 14. A law stating that the total pressure of a gas mixture equals the sum of the partial pressures of each individual gas: Ptotal = P1 + P2 + P3 + ... + Pn
- 15. The normal, quiet breathing rate of approximately 12-15 breaths per minute.
- 16. The movement of gases between the atmosphere and the alveoli; the physical process of breathing air in and out of the lungs.
- 17. A region in the pons that facilitates smooth transitions between inspiration and expiration; damage to it causes erratic breathing.
Down
- 2. Hemoglobin that is bound to and transporting oxygen molecules.
- 3. The phenomenon where the unloading of oxygen from hemoglobin causes a conformational change that increases hemoglobin's capacity to bind carbon dioxide.
- 6. A law stating that the concentration of a gas dissolved in a liquid is proportional to its partial pressure above that liquid.
- 7. The primary method of carbon dioxide transport in the blood (~70%), where CO2 is converted to bicarbonate ion via carbonic anhydrase: CO2 + H20 <--> H2CO3 <--> H+ + HCO3-
- 8. A state in which ventilation exceeds the metabolic demands of the tissues, resulting in increased arterial O2 and decreased arterial CO2, potentially leading to respiratory alkalosis.
- 9. A state in which ventilation does not meet the demands of the tissues, resulting in decreased arterial O2 and increased arterial CO2, potentially leading to respiratory acudisus,
- 10. A gas law stating that pressure and volume are inversely related; if volume increases, pressure decreases, and vice versa. This principle underlies the mechanics of breathing.
- 11. The exchange of repiratory gases between the blood in systemic capillaries and the body's systemic cells.
