Rheumatoid Arthritis Puzzle

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Across
  1. 4. RA is a systemic ________ disease
  2. 8. RH factor belongs to this class of antibodies
  3. 10. DNA modifications that regulates gene expression
  4. 12. Immune cells that play an key role in RA progression
  5. 13. Infection with this virus increases the risk of RA and belongs to herpes virus
Down
  1. 1. Cells that make new bone
  2. 2. It helps reduce friction between the joints
  3. 3. Increases the risk for both cardiovascular disease and RA
  4. 5. Formed by the action of PAD on arginine
  5. 6. Non coding RNA that play an important role in gene expression
  6. 7. Activation of JAK results in ______ of a protein
  7. 9. Dental condition associated with increased RA risk
  8. 11. Cells that breaks down bone